Point Of Care Testing of Ionized Magnesium in Blood with Potentiometric Sensors - Opportunities and Challenges
نویسنده
چکیده
Magnesium assays are being increasingly requested in hospitals and clinical research institutions. The ionized form of magnesium (iMg) is regarded as the biologically active fraction. Ionophore-based potentiometric sensors can determine iMg and apply a selectivity correction for co-existing interfering electrolytes, e.g. Ca 2+ . This technology has been used in several commercial blood analyzers for measuring iMg in whole blood samples. This report reviews the utility of iMg in clinical settings with emphasis on point of care (POC) application, potentiometric Mg 2+ sensor technology and challenges and opportunities for future ionized magnesium assays.
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